Hormone whodunit: clues for solving the case of intratumor androgen production.
نویسنده
چکیده
One of the key mechanisms by which prostate cancer cells evade hormone therapy is through intratumor testosterone production. New evidence points toward androstenedione as a potential precursor of intratumor androgen production and furthers nomination of AKR1C3 as a therapeutic target in advanced disease.
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ورودعنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 20 21 شماره
صفحات -
تاریخ انتشار 2014